First 3.4 Å TRPV1 structure solved by cryo-EM

First 3.4 Å TRPV1 structure solved by cryo-EM

K2 Summit camera was used to determine the structure of a mammalian TRP channel, TRPV1, at 3.4 Å resolution, breaking the side-chain resolution barrier for membrane proteins without crystallization. Nature 504, 107–112, 2013