Cryoplunge 3 System

Semi-automated plunge freezing instrument.

Advantages Research Spotlight Media Library Publications Resources Back to top

Cryoplunge® 3 system with GentleBlot™ technology is used for the preparation of frozen hydrated specimens for cryo-electron microscopy (cryo-EM).

  • GentleBlot technology optimizes blotting force and pressure to provide gentle 1- and 2-sided blotting to minimize breakage of fragile specimen supports
  • Humidified plunging chamber safeguards the specimen from drying during the blotting process
  • Temperature controlled pot maintains the condensed ethane at its melting point
  • Specially designed quick disconnect mechanism on plunge rod allows fast and easy attachment of the plunge tweezers to facilitate specimen handling
  • Removable liquid nitrogen workstation provides a contamination free environment to protect the frozen hydrated specimen


Nature Communications

Radamaker, L.; Lin, Y. -H.; Annamalai, K.; Huhn, S.; Hegenbart, U.; Schönland, S. O.; Fritz, G.; Schmidt, M.; Fändrich, M.


Kam, J.; Demmert, A. C.; Tanner, J. R.; McDonald, S. M.; Kelly, D. F.


Balasubramaniam, S.; Kayandan, S.; Lin, Y. N.; Kelly, D. F.; House, M. J.; Woodward, R. C.; St. Pierre, T. G.; Riffle, J. S.; Davis, R. M.

Back to top