GIF Quantum LS Imaging Filter

Maximize your resolution and contrast for cryo-EM by combining low distortion GIF Quantum optics with a K2 Summit detector that offers a “frame rate 10x higher than other[s]” and produces “a DQE as high as 80%.”

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Advantages: 

The GIF Quantum® LS imaging filter provides fundamental insights into cellular organization and ultrastructure by combining high performance energy filtration with direct detection technology. Ideally suited for low dose imaging applications, researchers can maximize their cryo-electron microscopy (cryo-EM) and cryo-electron tomography capabilities to gain further insight into complex systems function and disease progression at the molecular level.

  • Bringing together the low distortion optics of the GIF Quantum energy filter and the performance of the K2 Summit®
  • Be confident while imaging smaller particles with a detective quantum efficiency (DQE) as high as 80% in conjunction with reasonably small exposure times
  • Maintain high contrast with thick samples with the industry leading energy filter
  • See more of your sample with a 4-fold increase in field of view
  • Extend unattended throughput with fully automated multi-tilt and -region acquisition 

Publications

International Union of Crystallography Journal
2016

Subramaniam, S.; Kühlbrandt, W.; Henderson, R.

Science
2015

Bartesaghi, A.; Merk, A.; Banerjee, S.; Matthies, D.; Wu, X.; Milne, J. L. S.; Subramaniam, S.

Nature
2014

Lu, P.; Bai, X.; Ma, D.; Xie, T.; Yan, C.; Sun, L.; Yang, G.; Zhao, Y.; Zhou, R.; Scheres, S. H.; Shi, Y.

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