出版物

Cryo-EM structures of SARS-CoV-2 spike without and with ACE2 reveal a pH-dependent switch to mediate endosomal positioning of receptor-binding domains

Cell Host & Microbe

2020

Zhou, T.; Tsybovsky, Y.; Gorman, J.; Rapp, M.; Cerutti, G.; Chuang, G. -Y.; Katsamba, P. S.; Sampson, J. M.; Schön, A.; Bimela, J.; Boyington, J. C.; Nazzari, A.; Olia, A. S.; Shi, W.; Sastry, M.; Stephens, T.; Stuckey, J.; Teng, I. -T.; Kwong, P. D

Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA

Molecular Cell

2020

Yuan, S.; Peng, L.; Park, J. J.; Hu, Y.; Devarkar, S. C.; Dong, M. B.; Shen, Q.; Wu, S.; Chen, S.; Lomakin, I. B.; Xiong, Y.

Coronavirus infection induces progressive restructuring of the endoplasmic reticulum involving the formation and degradation of double membrane vesicles

Virology

2020

Mihelc. E. M.; Baker, S. C.; Lanman, J. K.

Spatial mapping of electrostatics and dynamics across 2D heterostructures

Condensed Matter

2020

Murthy, A. A.; Stanev, T. K.; Ribet, S. M.; Liu, P.; Watanabe, K.; Taniguchi, T.; Stern, N. P.; dos Reis, R.; Dravid, V. P.

They spent 12 years solving a puzzle. It yielded the first COVID-19 vaccines.

National Geographic

2020

Kramer, J.

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

ScienceAdvances

2021

Xu, C.; Wang, Y.; Liu, C.; Zhang, C.; Han, W.; Hong, X.; Wang, Y.; Hong, Q.; Wang, S.; Zhao, Q.; Wang, Y.; Yang, Y.; Chen, K.; Zheng, W.; Kong, L.; Wang, F.; Zuo, Q.; Huang, Z.; Cong, Y.

Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis

Cell

2021

Yan, L.; Ge, J.; Zheng, L.; Zhang, Y.; Gao, Y.; Wang, T.; Huang, Y.; Yang, Y.; Gao, S.; Li, M.; Liu, Z.; Wang, H.; Li, Y.; Chen, Y.; Guddat, L. W.; Wang, Q.; Rao, Z.; Lou, Z.

Stabilizing the closed SARS-CoV-2 spike trimer

Nature Communications

2021

Juraszek, J.; Rutten, L.; Blokland, S.; Bouchier, P.; Voorzaat, R.; Ritschel, T.; Bakkers, M. J. G.; Renault , L. L. R.; Langedijk, J. P. M.

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

Nature Communications

2021

Zhang, C.; Wang, Y.; Zhu, Y.; Liu, C.; Gu, C.; Xu, S.; Wang, Y.; Zhou, Y.; Wang, Y.; Han, W.; Hong, X.; Yang, Y.; Zhang, X.; Wang, T.; Xu, C.; Hong, Q.; Wang, S.; Zhao, Q.; Qiao, W.; Zang, J.; Kong, L.; Wang, F.; Wang, H.; Qu, D.; Lavillette, D.; Tang, H.; Deng, Q.; Xie, Y.; Cong, Y.; Huang, Z.

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

Nature Communications

2021

Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Höbartner, C.; Cramer, P.

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