NUANCE mission is to provide and continually update state-of-the-art and core analytical characterization instrumentation resources, with 24/7 open access, for the NU community and beyond. The word “resource” includes not only mere “instrumentation and access,” but also hands-on training, education, research collaboration and outreach. NUANCE aspires to be a pro-active and integral part of all scholarly activities related to characterization at and beyond NU.