Enhancing MicroED/3DED analysis with direct detection electron counting cameras 

Gatan instruments

The Metro^® camera enables low-dose imaging and diffraction via real-time electron counting with a simple user interface.

Background

PPEA, a semiconducting molecule, exhibits a high affinity to graphene surfaces. The PPEA molecule forms very small, needle-like crystals that measure several micrometers in length and have a width ranging from 100 to 200 nm. Due to their size, these crystals are too small for analysis using single-crystal x-ray structure techniques. Moreover, the beam-sensitive nature of PPEA requires low-dose techniques in the transmission electron microscope (TEM) to avoid damaging the crystallites, making continuous diffraction tomography (MicroED/3DED) the method of choice for structure determination.