MTF Curves

In cryo-electron microscopy (cryo-EM), the modulation transfer function (MTF) plays a pivotal role in determining the accuracy and clarity of the final reconstructed images. Download our expertly measured MTF curves to enhance your imaging workflow and achieve atomic-level insights.

• Signal preservation: High MTF ensures sharper atomic details; low MTF leads to blurred features like side chains or ligand sites.
• Detector performance: Direct electron detectors like the K3 offer superior MTF, reducing noise and enhancing contrast for accurate 3D reconstructions.
• Image processing: Data supports CTF correction, map sharpening, and Fourier filtering to restore contrast and improve map fidelity.
• Resolution validation: MTF ensures FSC-based resolution estimates reflect true structural detail, not artifacts.
• Structural biology impact: Poor MTF can cause misinterpretation of molecular interactions and reduce confidence in drug design.