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Dose fractionation and motion correction
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BioContinuum HD Imaging Filter
Model 1067HD
The best-in-class imaging filter for cryo-EM is now available with EELS and EFTEM.
Advantages
Introducing the BioContinuum® HD – The only fully-featured, post-column imaging and energy filter for life and material science applications. The BioContinuum HD provides zero-loss filtering to improve the contrast of transmission electron microscope (TEM) images and can be upgraded with the capability to acquire electron energy loss spectroscopy (EELS) and energy-filtered transmission electron microscopy (EFTEM) data.
The BioContinuum HD combines the latest generation of GIF electron optics, the K3® camera's transformative direct detection technology, and world-class EELS and EFTEM acquisition and analysis capabilities. This powerful combination of energy filter, camera, and software is optimized for cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), low-dose STEM spectrum imaging, EELS, and EFTEM. With the BioContinuum HD, you can successfully gain insight into the atomic structure of biological macromolecules, disease progression at the molecular level, and broaden your research to applications at the convergence of life and material science.
Providing the most easy-to-use and versatile system, the BioContinuum HD imaging filter can be controlled by the powerful DigitalMicrograph® software including STEMPack™ spectrum imaging, Latitude® S, Latitude T, and Latitude D. Alternatively, the BioContinuum imaging filter can be integrated into Thermo Scientific EPU software, Thermo Scientific Tomography software, Serial EM, and Leginion for traditional life science data collection.
The BioContinuum imaging filter is available in two different models:
BioContinuum | BioContinuum HD | |
|---|---|---|
| Model number | 1067 | 1067HD |
| Detector | K3 | K3 |
| Real-time motion correction | Optional | Optional |
| Integrated centered beam stop | Optional | Optional |
| EELS capability | – | Optional |
| EFTEM capability | – | Optional |
| Integrated BF/DF detector for STEM imaging | – | Optional |
The BioContinuum HD imaging filter is compatible with most TEMs from Thermo Fisher, JEOL, and Hitachi.
Easy to use
High-quality, high-throughput direct detection imaging
Stable, aberration-corrected optics
Versatile upgrade path
Datasheets
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