Introducing Alpine™, the world’s first direct detection camera to democratize cryo-electron microscopy (cryo-EM) imaging. By enabling the acquisition of high-resolution structures on 100 – 200 keV microscopes, Alpine allows routine cryo-EM research on more affordable, workhorse instruments and expands its usefulness to the larger research community.
- Delivers a detective quantum efficiency (DQE) up to 2.4-times the performance of scintillator-based cameras
- Routinely collects high-resolution data from 100 – 200 keV to convert screening microscopes into data collection microscopes
- Makes the 2D classification of small molecules possible while improving macromolecule reconstructions
- Streamlines your workflow and detects failures early to produce better structures, faster
- Real-time counting ensures there is no compromise between data collection speed and quality
Alpine Direct Detection Camera
Dose fractionation and motion correction
Improving DQE with counting and super-resolution
BioContinuum™ Imaging Filter
Latitude® S Software
Elsa™ Cryo-Transfer Holder
Continuing our prosperous collaborations that built the K2® and K3, Alpine is the successful result of Peter Denes' team at Lawrence Berkeley National Laboratory and David Agard.
Furthermore, Alpine is the result of prosperous collaborations with Gabe Lander's team at The Scripps Research Institute.